I agree that the timing between mineral fungicide application and holistic (with biological component) application addresses this to a degree. Leaf curl fungi utilize a
bud-savvy overwintering strategy and thus effectiveness with dormant copper requires getting this application to exposed bud scales before tissue growth begins in earnest. This can be a micronized copper or copper soap product (which more often is reserved for use directly on foliage). Time passes; rains fall. The amount of rainfall may not be as pertinent, however, as where the copper lodges for the duration. Let's include twig lesions and bark crevices as part of this discussion now. Dormant copper is used as well to lessen brown rot pressure overwintering in twig lesions on stone fruits. Similarly, copper on apple and pear targets fire blight bacterium disseminating to bark crevices and (in warmer places) scab conidia overwintering in the bud scales as a result of late fall rains. A good copper formulation is going to hold fast in all such nooks and crannies. That's the point. More exposed tree surfaces and expanding foliage tissue -- along with the ground surface in the case of Spring1 -- is going to be the "other target" for colonizing with friendly organisms. That's the way to think about this.
It's tempting to change the title here to talk even more broadly about mineral fungicides and arboreal biology. The use of copper soap within the growing season on fire blight sensitive cultivars being one example. Especially sulfur as a scab management tool. Different targets, different surfaces. Microbes are dynamic, with populations constantly shifting in response to conditions and available nutrient resources. Anyhow, I did add "dormant" to your title, David, thinking it important to distinguish this as an early season answer.
Lost Nation OrchardZone 4b in New Hampshire